In what could spell real trouble for the country in the next three months, a new report from prestigious Johns Hopkins University and the Centre for Disease Dynamics, Economics & Policy (CDDEP) has predicted that 21-day lockdown may be ineffective to stop the COVID-19 peak arriving in April-May-June — infecting over 12 crore Indians in an optimistic (low) scenario. In a High scenario (trajectory with current lockdowns but insufficient physical distancing or compliance), the total number of cases (asymptomatic, hospitalized and symptomatic) can even touch a massive figure of 25 crore. In the most likely (Medium) scenario with moderate to full compliance but no change in virulence or temperature/humidity sensitivity, the numbers of total cases can swell up to 18 crore. The optimistic (low) scenario constitutes decreased virulence and temperature/humidity sensitivity. To reach these numbers, Johns Hopkins and CDDEP — a public health research organisation — used IndiaSIM, a well-validated agent-based model of the Indian population which has been published widely over many years and has been used for government decision-making. According to the report, hospitalised cases can reach up to 25 lakh people in the High scenario, 17-18 lakh people in Medium scenario and 13 lakh people in Low scenario. “Ventilator demand will be 1 million. Current availability in India is estimated to be between 30,000 and 50,000 ventilators,” said the joint report.